Spectrum® Laboratories, Inc. features the widest array of Hollow Fiber Filters and systems for nanoparticle purification.
"Hollow Fiber Filtration with Spectrum's KrosFlo® Filters has been shown to be a proven method for nanoparticle (lipoplexes, polyplexes, and lipopolyplexes) purification," said David Serway Vice President of Business Development at Spectrum Laboratories. "Hollow fiber filtration has the distinct advantage of being easy to scale-up with as well as providing higher yields of purification. Optimal processing parameters determined at the R&D phase of development can be used in full-scale production."
The advantages of Hollow Fiber Filtration over traditional methods of nanoparticle purification include scalability, faster processing, easier colloidal clean up, and less time monitoring the process.
The wide ranges of pore size, ranging from 1nm to 500nm, make Hollow Fibers Filters useful in the majority of nanoparticle purification processes. In addition to pore size selection, hollow fiber technology also offers different membrane chemistries that are compatible with alcohols and low or high pH materials. Polysulfone and Polyethersulphone are two types of membranes that have wide applications in hollow fiber nanofiltration.
Hollow fiber filters are a proven purification technology for carbon nanotubes, silver colloids, gold particles, anilines, siRNA, liposomes, viruses, latex microspheres, ink, and many other colloidal complexes (particles).
Spectrum Laboratories, Inc.
Spectrum Laboratories manufactures a complete line of Disposable Bioprocess Separation Products. Spectrum's KrosFlo process filtration products include the largest selection of disposable hollow fiber filters and filtration systems for Tangential Flow Filtration for volumes from 2 mL to 10,000 L. Spectrum also offers disposable sterile process containment products, including bags, tank liners and custom tubing and manifold assemblies. Spectrum offers custom disposable and sterile filtration flow-path TFF systems (UF and MF) with detachable processing bags. For more information visit http://www.spectrumlabs.com