Sunday, May 23, 2010

Magnetic Nanoparticles Stabilized With Plant Extracts for Drug Delivery and Medical Applications

Iranian pharmacists managed to synthesize stabilized magnetic nanoparticles by plants extracts through green synthesis method for medical and drug delivery applications.

Fe3O4 magnetic nanoparticles have different applications especially in medical sciences. For optimum use, their surfaces should be stabilized and ready to be attached to drugs and other materials.

Dr. Ahmadreza Shahverdi, a member of Department of Pharmaceutical Biotechnology and Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, coated Fe3O4 nanoparticles with gold by hydro-alcoholic extract of eucalyptus.

"Using plants extracts or the method called 'Green Synthesis' causes gold ion reduction in the presence of Fe3O4 magnetic nanoparticles as well as containing surfaces with chemical functional groups like carboxyl", he said in an interview with INIC news service.

Elaborating on the function of herbal reductants, he reiterated, "Many of reductants lose their gold reductive ability when are tested in the presence of Fe3O4 synthesized nanoparticles or they could be utilized for gold reduction under more complicated conditions. However, using eucalyptus extract isn't bound to the mentioned problems."

"Our accomplishment is currently confined to the synthesis of Fe3O4-gold nanocomposite and we are proceeding with conducting new researches on isolation of gold-coated magnetite Fe3O4 form from these nanocomposites which have more reliable resistance and stability in different physicochemical conditions," Shahverdi added.

For more details see Journal of Nanomaterials, code 962021, pages 1-5.

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